【1104 Seminar】Intergenerational Transmission of Human Brain Networks: Taking Reading (and Emotion-Regulation) Networks as Examples :::

演講日期:2014-11-04

Speaker
Fumiko Hoeft, M.D., Ph.D.
Director of brainLENS & Associate Professor of of Psychiatry at UCSF
Research Scientist, Haskins Laboratories

Title
Intergenerational Transmission of Human Brain Networks: Taking Reading (and Emotion-Regulation) Networks as Examples

Time
11/04 Tuesday 14:00 - 16:00

Venue
3rd conference room of Auditorium and Activity Center, NYMU

Abstract
Major higher-level cognition, complex traits and neuropsychiatric disorders show intergenerational transmission patterns. These effects can occur at the genetic, prenatal and postnatal level, and dissection of these transmission patterns have the potential to reveal the neurobiological substrates of human cognition and psychopathology. To date however, evidence in the human brain remains elusive. In the current talk, I will present novel approaches, i.e., intergenerational imaging and natural cross-fostering designs. I will also present preliminary evidence of sex-specific transmission patterns and patterns consistent with the multiple deficit model, that both parents confer risk. Examples will be drawn mostly from the field of reading, but also in the cortico-limbic circuit to validate our approach. Such research could provide critical information not only about the neurobiological mechanism underlying reading and emotion-regulation but also may inform clinical and educational practices.