Speaker:
Dr. John H.K. Liu, PhD
Professor, Department of Ophthalmology, UCSD
Topic:
Lessons from my works on intraocular pressure
Venue:
Science Building #4, S4-209, NCU (中央大學科四館209室)
Date & Time:
2018/10/16, 14:30~16:00
Abstract:
From my training in graduate school to the years of 1996-1998, I did biochemical research on signal transduction using ocular tissues involved in the regulation of intraocular pressure (IOP). I also did in vivo physiological research on neural and hormonal regulation of IOP in various animal species. These works led me to concentrate my research on the circadian (24-hour) rhythm of IOP. Having known that our knowledge of 24-hour IOP in humans was insufficient, I began to organize a research team 1996-1998 to work on 24-hour IOP in humans using the campus sleep laboratory at UC San Diego. The emphasis was on the nocturnal IOP in various clinical conditions including healthy eyes, eyes with ocular hypertension, untreated glaucomatous eyes and eyes treated with glaucoma medications and laser surgery. Our works provided the foundation for others to commercialize the first human 24-hour IOP monitor using a contact lens based biosensor. I will share with you my lessons from these works.